1 Foetus weight at birth

data(birthweight, package="isdals")
weight <- birthweight$weight
weight
##  [1] 2968 2795 3163 2925 2625 2847 3292 3473 2628 3176 3421 2975 3317 2729
## [15] 2935 2754 3210 2817 3126 2539 2412 2991 2875 3231
qplot(weight)
## `stat_bin()` using `bins = 30`. Pick better value with `binwidth`.

The task is to estimate the mean weight of foetuses in a “population”; let us call this true but unknown quantity for \(\mu\). Based on the data above, the average would be one such estimate: \[ \hat\mu = (y_1 + \dots + y_N)/N \]

mean(weight)
## [1] 2967.667

The standard deviation is a measure of the spread of data

sd(weight)
## [1] 282.0633

Remember the practical interpretation of standard deviation

(max(weight) - min(weight))/4
## [1] 265.25

1.1 Confidence intervals

In addition to having an estimate of the mean, it is often (if not always) desirable to obtain some sort of interval in which we with a certain degree of certainty can say that the true population mean belongs. This leads to confidence intevals.

Let us assume that each observation is the outcome of a normal variable \(Y_i \sim N(\mu,\sigma^2), i=1,\dots, N\).

Then we know that \(\bar Y = (Y_1 + \dots Y_N)/N\) is normal \[ \bar Y \sim N(\mu, SE) \] where \(SE=\sigma^2/N\).

We know that about \(95%\) of the probability mass (or observations) in a normal distribution \(N(\mu,\sigma^2)\) is within the range fram \(\mu-2\sigma\) to \(\mu + 2\sigma\) (actually we should write \(1.96\) rather than \(2\) but that is not important here.). That is

\[ Pr(\mu-2\sigma \le Y \le \mu + 2\sigma) \approx 0.95 \] Rearranging this give

\[ Pr(Y-2\sigma \le \mu \le Y + 2\sigma) \approx 0.95 \]

Notice: The random part above is \(Y\) and so are the end points of the interval \[ [Y-2\sigma; Y+2s\sigma] \] Suppose \(Y \sim N(\mu, 2^2)\) (so \(\sigma\) is known, just for simplicity). Now, observe \(y_1\), and we computed the interval

sigma <- 2

y1 <- 4.5
c(y1 - 2 * sigma, y1 + 2 * sigma)
## [1] 0.5 8.5
y2 <- 7.1
c(y2 - 2 * sigma, y2 + 2 * sigma)
## [1]  3.1 11.1

Now we play the simulation game: \(Y \sim N(\mu, 2^2)\) where we suddenly have divine insight and “know” that \(\mu=10\).

set.seed(14)
M <- 20
mu <- 10
y <- rnorm(M, mean=10, sd=sigma)
ci <- cbind(y - 2 * sigma, y + 2 * sigma)
ci
##            [,1]     [,2]
##  [1,]  4.676300 12.67630
##  [2,]  9.437908 17.43791
##  [3,] 10.243334 18.24333
##  [4,]  8.994307 16.99431
##  [5,]  5.927719 13.92772
##  [6,]  8.463890 16.46389
##  [7,]  5.870238 13.87024
##  [8,]  8.137987 16.13799
##  [9,]  5.246069 13.24607
## [10,]  8.086366 16.08637
## [11,]  5.234356 13.23436
## [12,]  6.598843 14.59884
## [13,]  7.348480 15.34848
## [14,]  5.414367 13.41437
## [15,]  6.976107 14.97611
## [16,]  7.765604 15.76560
## [17,]  9.725498 17.72550
## [18,]  9.223451 17.22345
## [19,]  6.270959 14.27096
## [20,]  8.176172 16.17617

Notice: For each observation we get an interval. The true value of the parameter (\(\mu=10\)) is either contained in an interval or it is not.

We call the intervals for 95% confidence intervals. It would not be correct to say an interval contains the true parameter with probability 95%: Either the parameter is contained in an interval or it is not.

However if we conduct the experiment many times and compute a confidence interval each time, then 95% of the intervals will contain the true parameter:

set.seed(14)
M <- 1000
mu <- 10
y <- rnorm(M, mean=10, sd=sigma)
ci <- cbind(y - 2 * sigma, y + 2 * sigma)
ci
##                [,1]      [,2]
##    [1,]  4.67630034 12.676300
##    [2,]  9.43790831 17.437908
##    [3,] 10.24333398 18.243334
##    [4,]  8.99430737 16.994307
##    [5,]  5.92771884 13.927719
##    [6,]  8.46389035 16.463890
##    [7,]  5.87023846 13.870238
##    [8,]  8.13798746 16.137987
##    [9,]  5.24606939 13.246069
##   [10,]  8.08636619 16.086366
##   [11,]  5.23435624 13.234356
##   [12,]  6.59884319 14.598843
##   [13,]  7.34847952 15.348480
##   [14,]  5.41436736 13.414367
##   [15,]  6.97610672 14.976107
##   [16,]  7.76560365 15.765604
##   [17,]  9.72549796 17.725498
##   [18,]  9.22345058 17.223451
##   [19,]  6.27095908 14.270959
##   [20,]  8.17617202 16.176172
##   [21,]  3.46637048 11.466370
##   [22,]  5.60283343 13.602833
##   [23,]  6.27773156 14.277732
##   [24,]  5.44132800 13.441328
##   [25,]  7.41783883 15.417839
##   [26,]  4.46677908 12.466779
##   [27,]  8.88672589 16.886726
##   [28,]  7.68975860 15.689759
##   [29,]  5.20125919 13.201259
##   [30,]  3.14446483 11.144465
##   [31,]  3.15601510 11.156015
##   [32,]  5.34354342 13.343543
##   [33,]  6.56914015 14.569140
##   [34,]  7.43867176 15.438672
##   [35,]  6.86483195 14.864832
##   [36,]  5.29615046 13.296150
##   [37,]  6.59544286 14.595443
##   [38,]  5.47713528 13.477135
##   [39,]  8.61737946 16.617379
##   [40,]  6.03174053 14.031741
##   [41,]  5.13765126 13.137651
##   [42,]  6.76489308 14.764893
##   [43,]  6.08225019 14.082250
##   [44,]  5.88155200 13.881552
##   [45,]  3.40715203 11.407152
##   [46,]  1.72604725  9.726047
##   [47,]  4.21277063 12.212771
##   [48,]  7.22546575 15.225466
##   [49,]  7.16594246 15.165942
##   [50,]  5.98823597 13.988236
##   [51,]  2.26910255 10.269103
##   [52,]  9.65996865 17.659969
##   [53,]  4.01776820 12.017768
##   [54,]  3.09913075 11.099131
##   [55,]  5.97035048 13.970350
##   [56,]  7.07327811 15.073278
##   [57,]  4.37779247 12.377792
##   [58,]  5.36335040 13.363350
##   [59,]  8.22295201 16.222952
##   [60,]  5.71651057 13.716511
##   [61,]  5.58924209 13.589242
##   [62,]  4.63840841 12.638408
##   [63,]  5.91401652 13.914017
##   [64,]  3.67689478 11.676895
##   [65,]  4.45461566 12.454616
##   [66,]  4.16252174 12.162522
##   [67,]  6.17830635 14.178306
##   [68,]  4.48492174 12.484922
##   [69,]  9.49616236 17.496162
##   [70,]  6.34092140 14.340921
##   [71,]  7.65106226 15.651062
##   [72,]  5.96568817 13.965688
##   [73,]  6.98444333 14.984443
##   [74,]  6.71097794 14.710978
##   [75,]  6.22515340 14.225153
##   [76,]  8.27405864 16.274059
##   [77,]  4.86611031 12.866110
##   [78,]  7.10523249 15.105232
##   [79,]  5.97499654 13.974997
##   [80,]  4.85757878 12.857579
##   [81,]  4.63144572 12.631446
##   [82,]  8.33861843 16.338618
##   [83,]  6.73893735 14.738937
##   [84,]  4.97853016 12.978530
##   [85,]  4.73691033 12.736910
##   [86,]  9.42655592 17.426556
##   [87,]  5.55399356 13.553994
##   [88,]  4.08220545 12.082205
##   [89,]  6.07549048 14.075490
##   [90,]  2.71698752 10.716988
##   [91,]  7.57998649 15.579986
##   [92,]  3.88573926 11.885739
##   [93,]  3.94214928 11.942149
##   [94,]  8.20185953 16.201860
##   [95,]  4.77218004 12.772180
##   [96,]  5.30823517 13.308235
##   [97,]  6.17198024 14.171980
##   [98,]  4.70136741 12.701367
##   [99,]  6.61192558 14.611926
##  [100,]  4.45709343 12.457093
##  [101,]  9.38258444 17.382584
##  [102,]  7.31737443 15.317374
##  [103,]  5.89000111 13.890001
##  [104,]  1.34423791  9.344238
##  [105,]  6.26453626 14.264536
##  [106,]  5.43329820 13.433298
##  [107,] 10.81400689 18.814007
##  [108,]  4.99914642 12.999146
##  [109,]  6.94367400 14.943674
##  [110,]  4.37196965 12.371970
##  [111,]  8.78872324 16.788723
##  [112,]  1.82232074  9.822321
##  [113,]  8.42788080 16.427881
##  [114,]  5.99342546 13.993425
##  [115,]  8.55592552 16.555926
##  [116,]  9.81113763 17.811138
##  [117,]  3.99838811 11.998388
##  [118,]  6.31365850 14.313658
##  [119,]  4.24286539 12.242865
##  [120,]  6.03313008 14.033130
##  [121,]  4.91072200 12.910722
##  [122,]  5.00691992 13.006920
##  [123,]  2.76328468 10.763285
##  [124,]  5.87372034 13.873720
##  [125,]  9.34648908 17.346489
##  [126,]  4.07314839 12.073148
##  [127,]  5.15197550 13.151976
##  [128,]  7.34869301 15.348693
##  [129,]  5.23843050 13.238431
##  [130,]  7.81482783 15.814828
##  [131,]  6.72533395 14.725334
##  [132,]  2.02057852 10.020579
##  [133,]  3.90789401 11.907894
##  [134,]  5.68479397 13.684794
##  [135,]  7.43659279 15.436593
##  [136,]  7.60546748 15.605467
##  [137,]  4.37145042 12.371450
##  [138,]  3.54628839 11.546288
##  [139,]  6.31528929 14.315289
##  [140,]  3.12557372 11.125574
##  [141,]  5.36114635 13.361146
##  [142,]  8.46844448 16.468444
##  [143,]  4.48321391 12.483214
##  [144,]  8.66955894 16.669559
##  [145,]  7.79302359 15.793024
##  [146,]  6.63688742 14.636887
##  [147,]  4.65946476 12.659465
##  [148,]  4.98345717 12.983457
##  [149,]  8.83371014 16.833710
##  [150,]  4.31181163 12.311812
##  [151,]  8.27765363 16.277654
##  [152,]  6.39498636 14.394986
##  [153,]  6.70159227 14.701592
##  [154,]  5.18477508 13.184775
##  [155,]  4.59192645 12.591926
##  [156,]  3.32036401 11.320364
##  [157,]  5.91193963 13.911940
##  [158,]  2.68320562 10.683206
##  [159,]  3.97492462 11.974925
##  [160,]  2.81694413 10.816944
##  [161,]  3.06986449 11.069864
##  [162,]  5.48645945 13.486459
##  [163,]  7.19864658 15.198647
##  [164,]  7.21778639 15.217786
##  [165,]  8.57316766 16.573168
##  [166,]  6.94368809 14.943688
##  [167,]  8.15452844 16.154528
##  [168,]  5.95354782 13.953548
##  [169,]  5.15415553 13.154156
##  [170,]  5.85934104 13.859341
##  [171,]  4.93997674 12.939977
##  [172,]  6.73578693 14.735787
##  [173,]  6.28671989 14.286720
##  [174,]  8.14373031 16.143730
##  [175,]  6.57048564 14.570486
##  [176,]  5.53950995 13.539510
##  [177,]  4.30970215 12.309702
##  [178,]  6.74544349 14.745443
##  [179,]  5.89089908 13.890899
##  [180,]  5.57936972 13.579370
##  [181,]  7.70336658 15.703367
##  [182,]  0.28102914  8.281029
##  [183,]  3.60240109 11.602401
##  [184,]  6.19205712 14.192057
##  [185,]  6.92433292 14.924333
##  [186,]  5.68827484 13.688275
##  [187,]  7.74993013 15.749930
##  [188,]  6.03948851 14.039489
##  [189,]  9.05847905 17.058479
##  [190,]  6.85938209 14.859382
##  [191,]  6.77527325 14.775273
##  [192,]  6.77796726 14.777967
##  [193,]  6.30413368 14.304134
##  [194,]  8.52445188 16.524452
##  [195,]  8.14857127 16.148571
##  [196,]  3.15748212 11.157482
##  [197,]  6.14131418 14.141314
##  [198,]  9.29657001 17.296570
##  [199,]  3.13787226 11.137872
##  [200,]  7.74795862 15.747959
##  [201,]  3.93825816 11.938258
##  [202,]  4.61319191 12.613192
##  [203,]  7.01307377 15.013074
##  [204,]  7.71956021 15.719560
##  [205,]  8.49454477 16.494545
##  [206,]  4.79370313 12.793703
##  [207,]  2.07069337 10.070693
##  [208,]  3.79977111 11.799771
##  [209,]  6.99301407 14.993014
##  [210,]  5.94001898 13.940019
##  [211,]  5.71265299 13.712653
##  [212,]  4.59815718 12.598157
##  [213,]  4.27277746 12.272777
##  [214,]  8.24894144 16.248941
##  [215,]  0.93171712  8.931717
##  [216,]  5.77865403 13.778654
##  [217,]  8.08107619 16.081076
##  [218,]  7.68339263 15.683393
##  [219,]  6.53589805 14.535898
##  [220,]  8.68619699 16.686197
##  [221,]  5.58806796 13.588068
##  [222,]  4.54374885 12.543749
##  [223,]  2.18503422 10.185034
##  [224,]  7.67792510 15.677925
##  [225,]  3.88732508 11.887325
##  [226,]  5.40805060 13.408051
##  [227,]  4.42348730 12.423487
##  [228,]  3.00911634 11.009116
##  [229,]  4.68269437 12.682694
##  [230,]  8.63115006 16.631150
##  [231,]  6.16008527 14.160085
##  [232,]  8.28974431 16.289744
##  [233,]  7.25047255 15.250473
##  [234,]  4.90341065 12.903411
##  [235,]  3.58002986 11.580030
##  [236,]  6.73193077 14.731931
##  [237,]  5.52935424 13.529354
##  [238,]  3.70009296 11.700093
##  [239,]  7.85772775 15.857728
##  [240,]  4.00973349 12.009733
##  [241,]  7.14070003 15.140700
##  [242,]  5.08901604 13.089016
##  [243,]  5.03716814 13.037168
##  [244,]  9.69897641 17.698976
##  [245,]  8.19726069 16.197261
##  [246,]  3.06618731 11.066187
##  [247,] 10.18452662 18.184527
##  [248,]  7.67964411 15.679644
##  [249,]  3.89917352 11.899174
##  [250,]  2.91989864 10.919899
##  [251,]  9.31123515 17.311235
##  [252,]  1.42497476  9.424975
##  [253,]  8.05328395 16.053284
##  [254,]  8.52323946 16.523239
##  [255,]  6.27068411 14.270684
##  [256,]  2.13929533 10.139295
##  [257,]  4.63395189 12.633952
##  [258,]  3.95530366 11.955304
##  [259,]  1.96297860  9.962979
##  [260,]  3.32780411 11.327804
##  [261,]  5.32952268 13.329523
##  [262,]  3.58899804 11.588998
##  [263,]  5.64620021 13.646200
##  [264,]  6.35216309 14.352163
##  [265,]  4.58811909 12.588119
##  [266,]  8.48363027 16.483630
##  [267,]  4.44263735 12.442637
##  [268,]  6.53961005 14.539610
##  [269,]  8.87968555 16.879686
##  [270,]  6.43452849 14.434528
##  [271,]  6.59438790 14.594388
##  [272,]  4.85681345 12.856813
##  [273,]  5.54990615 13.549906
##  [274,]  3.54324753 11.543248
##  [275,]  6.11195859 14.111959
##  [276,]  5.11384661 13.113847
##  [277,]  5.97285725 13.972857
##  [278,]  5.59552999 13.595530
##  [279,]  6.43787311 14.437873
##  [280,]  7.04258813 15.042588
##  [281,]  2.81768514 10.817685
##  [282,]  5.35040624 13.350406
##  [283,]  3.22243614 11.222436
##  [284,]  3.01017856 11.010179
##  [285,]  6.74683391 14.746834
##  [286,]  3.96633871 11.966339
##  [287,] 10.87938937 18.879389
##  [288,]  6.55083460 14.550835
##  [289,]  6.26224310 14.262243
##  [290,]  7.93441596 15.934416
##  [291,]  3.81279613 11.812796
##  [292,]  5.93190711 13.931907
##  [293,]  5.13475854 13.134759
##  [294,]  3.24843872 11.248439
##  [295,]  7.93985250 15.939853
##  [296,]  3.43054913 11.430549
##  [297,]  5.43396301 13.433963
##  [298,]  6.44368859 14.443689
##  [299,]  8.64299454 16.642995
##  [300,]  3.16650451 11.166505
##  [301,] 10.47584787 18.475848
##  [302,]  4.84983111 12.849831
##  [303,]  4.57165802 12.571658
##  [304,]  6.04118957 14.041190
##  [305,]  4.29203694 12.292037
##  [306,] 11.35063887 19.350639
##  [307,]  6.28785063 14.287851
##  [308,]  5.80143476 13.801435
##  [309,]  8.18877396 16.188774
##  [310,]  4.55700870 12.557009
##  [311,]  4.73210296 12.732103
##  [312,]  4.36689758 12.366898
##  [313,]  5.99730491 13.997305
##  [314,]  6.57527958 14.575280
##  [315,]  3.59638310 11.596383
##  [316,]  9.77510436 17.775104
##  [317,]  3.83052150 11.830521
##  [318,]  5.04708692 13.047087
##  [319,]  7.82864405 15.828644
##  [320,]  2.17461915 10.174619
##  [321,]  3.67515416 11.675154
##  [322,]  6.52836706 14.528367
##  [323,]  3.19780899 11.197809
##  [324,]  4.38842668 12.388427
##  [325,]  5.01963530 13.019635
##  [326,]  6.01047055 14.010471
##  [327,]  3.77329047 11.773290
##  [328,]  3.89293492 11.892935
##  [329,]  6.27609644 14.276096
##  [330,]  2.23593105 10.235931
##  [331,]  5.69775681 13.697757
##  [332,]  5.01056153 13.010562
##  [333,]  6.63059047 14.630590
##  [334,]  4.32758774 12.327588
##  [335,]  5.62924294 13.629243
##  [336,]  9.67523721 17.675237
##  [337,]  5.53516973 13.535170
##  [338,]  6.43919523 14.439195
##  [339,]  9.54968394 17.549684
##  [340,]  5.46225479 13.462255
##  [341,]  8.79415328 16.794153
##  [342,]  7.45310815 15.453108
##  [343,]  4.64118450 12.641184
##  [344,]  6.95815396 14.958154
##  [345,]  3.67260505 11.672605
##  [346,]  7.12201093 15.122011
##  [347,]  3.05320095 11.053201
##  [348,]  8.87991773 16.879918
##  [349,]  5.43798453 13.437985
##  [350,]  5.11409424 13.114094
##  [351,]  8.11949023 16.119490
##  [352,]  4.38503607 12.385036
##  [353,]  5.86696347 13.866963
##  [354,]  9.94184216 17.941842
##  [355,]  6.17568422 14.175684
##  [356,]  3.96922799 11.969228
##  [357,] 10.86209534 18.862095
##  [358,] 11.26499773 19.264998
##  [359,]  6.92684637 14.926846
##  [360,]  3.89536048 11.895360
##  [361,]  8.08114039 16.081140
##  [362,]  5.15118904 13.151189
##  [363,]  2.95430337 10.954303
##  [364,]  7.13924647 15.139246
##  [365,]  7.21594426 15.215944
##  [366,]  4.62055097 12.620551
##  [367,]  5.71968449 13.719684
##  [368,]  3.42986557 11.429866
##  [369,]  3.44518814 11.445188
##  [370,]  9.56544896 17.565449
##  [371,]  7.32485688 15.324857
##  [372,]  6.39605564 14.396056
##  [373,]  7.95459154 15.954592
##  [374,]  5.27628634 13.276286
##  [375,]  1.87463663  9.874637
##  [376,]  3.35882009 11.358820
##  [377,]  9.33542134 17.335421
##  [378,]  6.69684620 14.696846
##  [379,]  4.74418984 12.744190
##  [380,]  7.09658352 15.096584
##  [381,]  8.65667416 16.656674
##  [382,]  7.24572084 15.245721
##  [383,]  6.71884769 14.718848
##  [384,]  8.14585059 16.145851
##  [385,]  7.40229376 15.402294
##  [386,]  5.97157659 13.971577
##  [387,]  6.42315913 14.423159
##  [388,]  3.64008783 11.640088
##  [389,]  4.69015290 12.690153
##  [390,]  5.69388216 13.693882
##  [391,]  1.76735118  9.767351
##  [392,]  5.47563846 13.475638
##  [393,]  4.48396258 12.483963
##  [394,]  5.40232688 13.402327
##  [395,]  8.28126424 16.281264
##  [396,]  7.73843408 15.738434
##  [397,]  3.42858565 11.428586
##  [398,]  3.51301275 11.513013
##  [399,]  5.08734146 13.087341
##  [400,]  6.67351147 14.673511
##  [401,]  4.28126195 12.281262
##  [402,]  8.75647119 16.756471
##  [403,]  8.05600748 16.056007
##  [404,]  5.03783084 13.037831
##  [405,]  8.20687778 16.206878
##  [406,]  9.57157336 17.571573
##  [407,]  5.19012455 13.190125
##  [408,]  4.46473463 12.464735
##  [409,]  2.83320285 10.833203
##  [410,]  4.05058685 12.050587
##  [411,]  9.45603808 17.456038
##  [412,]  2.74767426 10.747674
##  [413,]  9.11651008 17.116510
##  [414,]  3.12280543 11.122805
##  [415,]  6.01383731 14.013837
##  [416,]  6.05191099 14.051911
##  [417,]  3.13128310 11.131283
##  [418,]  0.85816316  8.858163
##  [419,]  8.50135988 16.501360
##  [420,]  4.05920801 12.059208
##  [421,]  2.25590474 10.255905
##  [422,]  1.82271310  9.822713
##  [423,]  4.74907675 12.749077
##  [424,]  8.73313755 16.733138
##  [425,]  5.33350462 13.333505
##  [426,]  4.71181229 12.711812
##  [427,]  6.24526817 14.245268
##  [428,]  5.67077748 13.670777
##  [429,]  2.52826461 10.528265
##  [430,] 10.68013963 18.680140
##  [431,]  6.86140674 14.861407
##  [432,]  7.18043457 15.180435
##  [433,]  5.21852869 13.218529
##  [434,]  3.37542677 11.375427
##  [435,]  6.43691879 14.436919
##  [436,]  5.11041169 13.110412
##  [437,]  5.90901438 13.909014
##  [438,]  7.33870611 15.338706
##  [439,]  7.58657079 15.586571
##  [440,]  4.12657247 12.126572
##  [441,]  1.98679632  9.986796
##  [442,]  7.92363759 15.923638
##  [443,]  8.18323666 16.183237
##  [444,]  7.47058130 15.470581
##  [445,]  3.93587587 11.935876
##  [446,]  6.85204427 14.852044
##  [447,]  7.76491522 15.764915
##  [448,] 11.00572388 19.005724
##  [449,]  3.35279327 11.352793
##  [450,]  7.85042312 15.850423
##  [451,]  6.52562180 14.525622
##  [452,]  6.06448268 14.064483
##  [453,]  9.15201328 17.152013
##  [454,]  9.05304883 17.053049
##  [455,]  8.29287094 16.292871
##  [456,]  6.12573672 14.125737
##  [457,]  4.24570673 12.245707
##  [458,]  3.06500935 11.065009
##  [459,]  3.56578059 11.565781
##  [460,]  4.43716286 12.437163
##  [461,]  3.89042638 11.890426
##  [462,] 10.37185961 18.371860
##  [463,]  5.65013369 13.650134
##  [464,]  9.25246480 17.252465
##  [465,]  5.13519605 13.135196
##  [466,]  4.89459466 12.894595
##  [467,]  2.15793369 10.157934
##  [468,]  4.67001134 12.670011
##  [469,]  6.85085279 14.850853
##  [470,]  5.44007635 13.440076
##  [471,]  9.98625771 17.986258
##  [472,]  6.85664935 14.856649
##  [473,]  4.14919047 12.149190
##  [474,]  7.93399772 15.933998
##  [475,]  6.34695793 14.346958
##  [476,]  6.41306376 14.413064
##  [477,]  2.64953459 10.649535
##  [478,]  6.13988461 14.139885
##  [479,]  5.74368639 13.743686
##  [480,]  6.63891988 14.638920
##  [481,]  9.95171732 17.951717
##  [482,]  6.36385831 14.363858
##  [483,]  7.93704389 15.937044
##  [484,]  4.86588388 12.865884
##  [485,]  4.49548811 12.495488
##  [486,]  0.34704362  8.347044
##  [487,]  3.97356993 11.973570
##  [488,]  7.15399724 15.153997
##  [489,]  7.68012632 15.680126
##  [490,]  6.20966219 14.209662
##  [491,]  5.12942879 13.129429
##  [492,]  6.37460528 14.374605
##  [493,]  9.28860403 17.288604
##  [494,]  4.50927798 12.509278
##  [495,]  7.99705526 15.997055
##  [496,]  5.60127845 13.601278
##  [497,]  6.34141065 14.341411
##  [498,]  7.43349629 15.433496
##  [499,]  4.55209785 12.552098
##  [500,]  4.21935052 12.219351
##  [501,]  6.34926416 14.349264
##  [502,]  2.83659894 10.836599
##  [503,]  9.15796030 17.157960
##  [504,]  7.59725842 15.597258
##  [505,]  3.12008787 11.120088
##  [506,]  7.10586684 15.105867
##  [507,]  6.98937127 14.989371
##  [508,]  3.23433741 11.234337
##  [509,]  6.70106534 14.701065
##  [510,]  8.26058600 16.260586
##  [511,]  8.63563795 16.635638
##  [512,]  4.52402055 12.524021
##  [513,]  3.24723337 11.247233
##  [514,]  5.11088892 13.110889
##  [515,]  5.86002273 13.860023
##  [516,]  0.81649251  8.816493
##  [517,]  5.76724257 13.767243
##  [518,]  5.99361360 13.993614
##  [519,]  5.59634633 13.596346
##  [520,]  4.47731131 12.477311
##  [521,]  4.32560354 12.325604
##  [522,]  5.20118333 13.201183
##  [523,]  1.70672128  9.706721
##  [524,]  1.37876876  9.378769
##  [525,]  5.13965466 13.139655
##  [526,]  6.81365044 14.813650
##  [527,]  5.72107233 13.721072
##  [528,]  3.41561991 11.415620
##  [529,]  6.01878221 14.018782
##  [530,]  3.58201174 11.582012
##  [531,]  4.25911604 12.259116
##  [532,]  4.91529231 12.915292
##  [533,]  5.24919201 13.249192
##  [534,]  4.89781973 12.897820
##  [535,]  6.21905229 14.219052
##  [536,]  6.39660576 14.396606
##  [537,]  3.56248875 11.562489
##  [538,]  4.54963599 12.549636
##  [539,]  4.52494301 12.524943
##  [540,]  9.33742385 17.337424
##  [541,]  4.71135522 12.711355
##  [542,]  7.03569649 15.035696
##  [543,]  6.64296958 14.642970
##  [544,]  3.99298254 11.992983
##  [545,]  5.09605845 13.096058
##  [546,]  3.43591002 11.435910
##  [547,]  2.49975102 10.499751
##  [548,]  2.94355593 10.943556
##  [549,]  8.42371815 16.423718
##  [550,]  7.59451108 15.594511
##  [551,]  5.53328179 13.533282
##  [552,]  6.80343160 14.803432
##  [553,]  6.07201502 14.072015
##  [554,]  6.06388741 14.063887
##  [555,] 11.28205550 19.282056
##  [556,]  5.08130148 13.081301
##  [557,]  8.61518389 16.615184
##  [558,]  7.78703289 15.787033
##  [559,]  4.01978211 12.019782
##  [560,]  8.03606235 16.036062
##  [561,]  2.17424814 10.174248
##  [562,]  5.34024362 13.340244
##  [563,]  5.55440787 13.554408
##  [564,]  3.96860154 11.968602
##  [565,]  8.17341588 16.173416
##  [566,]  4.93067299 12.930673
##  [567,]  8.16968086 16.169681
##  [568,]  3.57714391 11.577144
##  [569,]  3.18738373 11.187384
##  [570,]  5.65442767 13.654428
##  [571,]  6.03120981 14.031210
##  [572,]  5.52962941 13.529629
##  [573,]  7.20808222 15.208082
##  [574,]  5.47862593 13.478626
##  [575,]  8.21015160 16.210152
##  [576,]  4.36838961 12.368390
##  [577,]  6.47838847 14.478388
##  [578,]  9.29385305 17.293853
##  [579,]  3.58004706 11.580047
##  [580,]  3.23990743 11.239907
##  [581,]  8.46360572 16.463606
##  [582,]  4.30189170 12.301892
##  [583,]  7.96667203 15.966672
##  [584,]  6.15740333 14.157403
##  [585,]  8.24668281 16.246683
##  [586,]  8.96207335 16.962073
##  [587,] 11.42629330 19.426293
##  [588,]  4.79679266 12.796793
##  [589,]  9.60181419 17.601814
##  [590,]  6.58688436 14.586884
##  [591,]  5.43915593 13.439156
##  [592,]  9.76946099 17.769461
##  [593,]  7.49398686 15.493987
##  [594,]  8.19777843 16.197778
##  [595,]  6.58673671 14.586737
##  [596,]  7.49672407 15.496724
##  [597,]  2.10876045 10.108760
##  [598,]  5.29618350 13.296184
##  [599,]  7.53520194 15.535202
##  [600,]  4.04090434 12.040904
##  [601,]  3.69508898 11.695089
##  [602,]  4.12852047 12.128520
##  [603,]  2.48683901 10.486839
##  [604,]  6.46888703 14.468887
##  [605,]  8.41738251 16.417383
##  [606,]  7.10693889 15.106939
##  [607,]  6.95819905 14.958199
##  [608,]  7.41205706 15.412057
##  [609,]  2.18731131 10.187311
##  [610,]  7.56420745 15.564207
##  [611,]  9.47196800 17.471968
##  [612,]  6.68236137 14.682361
##  [613,]  4.88433472 12.884335
##  [614,]  2.66586179 10.665862
##  [615,]  4.65041794 12.650418
##  [616,]  6.54379489 14.543795
##  [617,]  7.62257999 15.622580
##  [618,]  6.10119822 14.101198
##  [619,]  4.79156409 12.791564
##  [620,]  4.40165268 12.401653
##  [621,]  7.57852826 15.578528
##  [622,]  8.03979642 16.039796
##  [623,]  7.49728135 15.497281
##  [624,]  7.20509223 15.205092
##  [625,]  1.94802263  9.948023
##  [626,]  4.97416028 12.974160
##  [627,]  6.63225128 14.632251
##  [628,]  8.52548178 16.525482
##  [629,]  3.84476353 11.844764
##  [630,]  7.34725295 15.347253
##  [631,]  6.78523976 14.785240
##  [632,]  5.94041596 13.940416
##  [633,]  5.81873589 13.818736
##  [634,]  6.79034051 14.790341
##  [635,]  3.27146320 11.271463
##  [636,]  4.59736711 12.597367
##  [637,]  2.01893238 10.018932
##  [638,]  7.88354792 15.883548
##  [639,]  7.27950911 15.279509
##  [640,]  9.06878794 17.068788
##  [641,]  3.55577404 11.555774
##  [642,]  8.11298820 16.112988
##  [643,]  4.04665456 12.046655
##  [644,]  5.06730315 13.067303
##  [645,]  4.90039532 12.900395
##  [646,]  2.27254946 10.272549
##  [647,]  6.66262408 14.662624
##  [648,]  3.05272870 11.052729
##  [649,]  6.04496816 14.044968
##  [650,]  4.67227984 12.672280
##  [651,]  4.68643658 12.686437
##  [652,]  3.63570389 11.635704
##  [653,]  6.81808353 14.818084
##  [654,]  6.70509261 14.705093
##  [655,]  4.08767455 12.087675
##  [656,]  3.95159823 11.951598
##  [657,]  5.03616278 13.036163
##  [658,]  3.94383629 11.943836
##  [659,]  4.41756534 12.417565
##  [660,]  6.12048896 14.120489
##  [661,]  5.70516779 13.705168
##  [662,]  8.31865938 16.318659
##  [663,]  2.16095135 10.160951
##  [664,]  8.07219518 16.072195
##  [665,]  9.40126027 17.401260
##  [666,]  5.67550238 13.675502
##  [667,]  7.26287701 15.262877
##  [668,]  5.97666009 13.976660
##  [669,]  5.49968087 13.499681
##  [670,]  4.99634897 12.996349
##  [671,]  6.58008189 14.580082
##  [672,]  8.84932346 16.849323
##  [673,]  6.94785081 14.947851
##  [674,]  9.74456514 17.744565
##  [675,]  8.28417754 16.284178
##  [676,]  3.50442640 11.504426
##  [677,]  7.79825366 15.798254
##  [678,]  6.80270927 14.802709
##  [679,]  3.35806959 11.358070
##  [680,]  5.66818145 13.668181
##  [681,]  5.53742341 13.537423
##  [682,]  4.46169989 12.461700
##  [683,]  9.47703244 17.477032
##  [684,]  0.07420639  8.074206
##  [685,]  3.61091298 11.610913
##  [686,]  7.06867837 15.068678
##  [687,]  7.35429155 15.354292
##  [688,]  6.90894024 14.908940
##  [689,]  4.29806251 12.298063
##  [690,]  9.01055010 17.010550
##  [691,]  7.36837691 15.368377
##  [692,]  4.95391477 12.953915
##  [693,]  8.15182713 16.151827
##  [694,]  8.90852565 16.908526
##  [695,]  7.57406202 15.574062
##  [696,]  3.43569118 11.435691
##  [697,]  7.93441735 15.934417
##  [698,]  6.22480510 14.224805
##  [699,] 10.62216917 18.622169
##  [700,]  5.20409207 13.204092
##  [701,]  9.15473805 17.154738
##  [702,]  6.75047192 14.750472
##  [703,]  6.95415559 14.954156
##  [704,]  9.27656569 17.276566
##  [705,]  5.09328294 13.093283
##  [706,]  6.28406752 14.284068
##  [707,]  4.06046922 12.060469
##  [708,]  3.67435593 11.674356
##  [709,]  2.76845613 10.768456
##  [710,]  6.21602347 14.216023
##  [711,]  3.36698355 11.366984
##  [712,]  8.53606529 16.536065
##  [713,]  6.49262624 14.492626
##  [714,]  6.57253788 14.572538
##  [715,]  5.15923037 13.159230
##  [716,]  8.84557058 16.845571
##  [717,]  1.98802373  9.988024
##  [718,]  3.19252272 11.192523
##  [719,]  8.12764056 16.127641
##  [720,]  6.06660159 14.066602
##  [721,]  5.25848443 13.258484
##  [722,]  9.86959845 17.869598
##  [723,]  6.23751852 14.237519
##  [724,]  7.03961021 15.039610
##  [725,]  6.82427414 14.824274
##  [726,]  4.44474903 12.444749
##  [727,]  4.54553765 12.545538
##  [728,]  4.61215950 12.612159
##  [729,]  4.80111567 12.801116
##  [730,]  4.65836349 12.658363
##  [731,]  4.57386636 12.573866
##  [732,]  5.28587917 13.285879
##  [733,]  6.57738418 14.577384
##  [734,]  3.24626374 11.246264
##  [735,]  4.17590819 12.175908
##  [736,]  7.86706887 15.867069
##  [737,]  8.96617347 16.966173
##  [738,]  6.97766014 14.977660
##  [739,]  7.42948808 15.429488
##  [740,]  5.11908034 13.119080
##  [741,]  9.15218789 17.152188
##  [742,]  3.83541818 11.835418
##  [743,]  3.92457706 11.924577
##  [744,]  3.34111132 11.341111
##  [745,]  7.57743202 15.577432
##  [746,]  5.40050781 13.400508
##  [747,]  3.67395899 11.673959
##  [748,] 11.84431581 19.844316
##  [749,]  5.49381165 13.493812
##  [750,]  5.23855329 13.238553
##  [751,]  7.62039304 15.620393
##  [752,] 10.02216324 18.022163
##  [753,]  5.69450032 13.694500
##  [754,]  7.88846059 15.888461
##  [755,]  7.52904469 15.529045
##  [756,]  3.91877127 11.918771
##  [757,]  5.86753507 13.867535
##  [758,]  9.75102618 17.751026
##  [759,]  9.26937825 17.269378
##  [760,]  7.88982998 15.889830
##  [761,]  6.80686032 14.806860
##  [762,]  5.41085282 13.410853
##  [763,]  4.76203462 12.762035
##  [764,]  4.82013574 12.820136
##  [765,]  9.80148214 17.801482
##  [766,]  3.78251546 11.782515
##  [767,]  7.23416805 15.234168
##  [768,]  6.05263721 14.052637
##  [769,]  4.83180195 12.831802
##  [770,]  4.70293895 12.702939
##  [771,]  5.52653707 13.526537
##  [772,]  6.04666684 14.046667
##  [773,]  9.39862945 17.398629
##  [774,]  2.44552519 10.445525
##  [775,]  2.39148355 10.391484
##  [776,]  4.49003838 12.490038
##  [777,]  3.96584736 11.965847
##  [778,]  6.57466283 14.574663
##  [779,]  6.72436844 14.724368
##  [780,]  4.00977622 12.009776
##  [781,]  1.53771207  9.537712
##  [782,]  7.29763131 15.297631
##  [783,]  4.87007283 12.870073
##  [784,]  5.81458614 13.814586
##  [785,]  7.18365609 15.183656
##  [786,]  0.64539734  8.645397
##  [787,] 11.26669934 19.266699
##  [788,]  7.61459508 15.614595
##  [789,]  8.40888693 16.408887
##  [790,]  4.03692377 12.036924
##  [791,]  7.55754612 15.557546
##  [792,]  7.09942912 15.099429
##  [793,]  9.29434092 17.294341
##  [794,]  4.07717000 12.077170
##  [795,] 11.15954008 19.159540
##  [796,]  3.71520663 11.715207
##  [797,]  5.28207434 13.282074
##  [798,]  2.28096912 10.280969
##  [799,]  9.44498226 17.444982
##  [800,]  6.40509339 14.405093
##  [801,]  7.61723993 15.617240
##  [802,]  5.81624215 13.816242
##  [803,]  3.91563932 11.915639
##  [804,]  7.39906138 15.399061
##  [805,]  7.04718098 15.047181
##  [806,]  3.29860240 11.298602
##  [807,]  5.26434744 13.264347
##  [808,]  6.74385030 14.743850
##  [809,]  2.60862606 10.608626
##  [810,]  1.85094596  9.850946
##  [811,]  6.66985887 14.669859
##  [812,]  4.74593993 12.745940
##  [813,]  8.00046582 16.000466
##  [814,]  5.86463868 13.864639
##  [815,]  5.38690987 13.386910
##  [816,]  6.88580670 14.885807
##  [817,]  8.07329005 16.073290
##  [818,]  4.81805563 12.818056
##  [819,]  8.13790344 16.137903
##  [820,]  5.42487753 13.424878
##  [821,]  8.21731714 16.217317
##  [822,]  3.61322000 11.613220
##  [823,] 10.31594805 18.315948
##  [824,]  7.01392930 15.013929
##  [825,]  5.22625130 13.226251
##  [826,]  6.24224397 14.242244
##  [827,]  9.72704970 17.727050
##  [828,]  5.62731278 13.627313
##  [829,]  4.20979634 12.209796
##  [830,]  5.22449985 13.224500
##  [831,]  4.03451776 12.034518
##  [832,]  6.15820687 14.158207
##  [833,]  3.02291036 11.022910
##  [834,] 10.06856847 18.068568
##  [835,]  8.82488630 16.824886
##  [836,]  5.15588611 13.155886
##  [837,]  6.26615410 14.266154
##  [838,]  4.18076654 12.180767
##  [839,]  5.45143310 13.451433
##  [840,]  2.01258241 10.012582
##  [841,]  6.77394187 14.773942
##  [842,]  5.78026522 13.780265
##  [843,]  3.71966712 11.719667
##  [844,]  7.04971351 15.049714
##  [845,]  6.90703767 14.907038
##  [846,]  6.44312762 14.443128
##  [847,]  8.54696584 16.546966
##  [848,]  6.14452547 14.144525
##  [849,]  5.01476117 13.014761
##  [850,]  7.13107236 15.131072
##  [851,]  8.55433246 16.554332
##  [852,]  9.60108235 17.601082
##  [853,]  1.61262386  9.612624
##  [854,]  2.28979435 10.289794
##  [855,]  9.38322258 17.383223
##  [856,]  2.04949629 10.049496
##  [857,]  6.87183697 14.871837
##  [858,]  6.38084060 14.380841
##  [859,]  8.64818637 16.648186
##  [860,]  4.63905016 12.639050
##  [861,]  5.37057421 13.370574
##  [862,]  6.26113564 14.261136
##  [863,]  5.72710243 13.727102
##  [864,]  8.47637743 16.476377
##  [865,]  4.37430572 12.374306
##  [866,]  6.59428113 14.594281
##  [867,]  5.14943755 13.149438
##  [868,]  5.74317465 13.743175
##  [869,]  6.80378984 14.803790
##  [870,]  7.97076365 15.970764
##  [871,]  8.90136162 16.901362
##  [872,]  9.22182165 17.221822
##  [873,]  3.87872586 11.878726
##  [874,]  6.61868417 14.618684
##  [875,]  5.74668125 13.746681
##  [876,]  5.16936075 13.169361
##  [877,]  3.86762289 11.867623
##  [878,]  7.63122380 15.631224
##  [879,]  6.32071460 14.320715
##  [880,]  5.64044234 13.640442
##  [881,]  3.80877598 11.808776
##  [882,]  5.84651064 13.846511
##  [883,]  6.56507014 14.565070
##  [884,]  1.76339068  9.763391
##  [885,]  4.90148367 12.901484
##  [886,]  6.24639853 14.246399
##  [887,]  3.78457760 11.784578
##  [888,]  6.45042852 14.450429
##  [889,]  1.99682283  9.996823
##  [890,]  3.25378768 11.253788
##  [891,]  8.16813093 16.168131
##  [892,]  5.13187328 13.131873
##  [893,]  4.87108338 12.871083
##  [894,]  5.24994320 13.249943
##  [895,]  4.93916993 12.939170
##  [896,]  7.17461899 15.174619
##  [897,]  4.68826128 12.688261
##  [898,]  5.80918756 13.809188
##  [899,]  0.74970103  8.749701
##  [900,]  4.59483808 12.594838
##  [901,]  7.76580313 15.765803
##  [902,]  7.12676514 15.126765
##  [903,]  8.09829215 16.098292
##  [904,]  6.63963241 14.639632
##  [905,]  3.78823212 11.788232
##  [906,]  4.45783438 12.457834
##  [907,]  6.95585328 14.955853
##  [908,]  5.35070265 13.350703
##  [909,]  7.17541328 15.175413
##  [910,]  2.94864258 10.948643
##  [911,]  8.41459816 16.414598
##  [912,]  5.15331078 13.153311
##  [913,]  7.58677461 15.586775
##  [914,]  6.22300643 14.223006
##  [915,]  7.04425664 15.044257
##  [916,]  5.03476446 13.034764
##  [917,]  5.75763751 13.757638
##  [918,]  6.46538812 14.465388
##  [919,] 10.41664229 18.416642
##  [920,]  5.75815935 13.758159
##  [921,]  5.45822878 13.458229
##  [922,]  9.05070004 17.050700
##  [923,]  5.45021652 13.450217
##  [924,]  9.09609980 17.096100
##  [925,]  8.18842951 16.188430
##  [926,]  7.93132175 15.931322
##  [927,]  3.11402186 11.114022
##  [928,]  7.46955219 15.469552
##  [929,]  6.49119812 14.491198
##  [930,]  8.04651629 16.046516
##  [931,]  4.19798811 12.197988
##  [932,]  4.88053228 12.880532
##  [933,]  6.72232076 14.722321
##  [934,]  9.19105201 17.191052
##  [935,]  4.33182715 12.331827
##  [936,]  4.10771035 12.107710
##  [937,]  6.92340903 14.923409
##  [938,]  9.06588837 17.065888
##  [939,]  7.37598838 15.375988
##  [940,]  4.15495596 12.154956
##  [941,]  5.56778528 13.567785
##  [942,]  8.21209216 16.212092
##  [943,]  1.90732003  9.907320
##  [944,]  1.04312928  9.043129
##  [945,]  4.11281091 12.112811
##  [946,]  6.40766824 14.407668
##  [947,]  7.37869381 15.378694
##  [948,]  4.34601701 12.346017
##  [949,]  5.30005186 13.300052
##  [950,]  7.85056648 15.850566
##  [951,]  7.98648746 15.986487
##  [952,]  7.20554888 15.205549
##  [953,]  7.70262761 15.702628
##  [954,]  5.83201136 13.832011
##  [955,]  8.02495296 16.024953
##  [956,] 11.46536792 19.465368
##  [957,]  5.91921050 13.919210
##  [958,]  7.88757868 15.887579
##  [959,]  7.35341892 15.353419
##  [960,]  2.96059808 10.960598
##  [961,]  4.58905473 12.589055
##  [962,]  6.81991117 14.819911
##  [963,]  6.77444742 14.774447
##  [964,]  5.54843117 13.548431
##  [965,]  6.82003762 14.820038
##  [966,]  5.60274427 13.602744
##  [967,]  7.52848449 15.528484
##  [968,]  6.74977245 14.749772
##  [969,]  6.02701841 14.027018
##  [970,]  4.57636990 12.576370
##  [971,]  2.88557283 10.885573
##  [972,]  9.41623480 17.416235
##  [973,]  6.62011346 14.620113
##  [974,]  4.99413302 12.994133
##  [975,]  5.72357185 13.723572
##  [976,]  5.95175073 13.951751
##  [977,]  6.96341087 14.963411
##  [978,]  5.30960969 13.309610
##  [979,]  4.64242226 12.642422
##  [980,]  8.06096324 16.060963
##  [981,]  5.38955743 13.389557
##  [982,]  2.11130015 10.111300
##  [983,]  7.23494989 15.234950
##  [984,]  6.27895182 14.278952
##  [985,]  7.50107313 15.501073
##  [986,]  4.41819452 12.418195
##  [987,]  8.09902397 16.099024
##  [988,]  3.73140943 11.731409
##  [989,]  4.12548557 12.125486
##  [990,]  7.04742547 15.047425
##  [991,]  6.83967846 14.839678
##  [992,]  5.20377222 13.203772
##  [993,]  6.37951688 14.379517
##  [994,]  5.36088847 13.360888
##  [995,]  3.87500961 11.875010
##  [996,] 10.41376834 18.413768
##  [997,]  5.07497731 13.074977
##  [998,]  5.64181559 13.641816
##  [999,]  6.24964267 14.249643
## [1000,]  4.19984832 12.199848
head(ci)
##           [,1]     [,2]
## [1,]  4.676300 12.67630
## [2,]  9.437908 17.43791
## [3,] 10.243334 18.24333
## [4,]  8.994307 16.99431
## [5,]  5.927719 13.92772
## [6,]  8.463890 16.46389
outside <- ci[,1] > mu | ci[,2] < mu
sum(outside)
## [1] 51
(M - sum(outside)) / M
## [1] 0.949